Al-Aloul Mohamed, Miller Helen, Stockton Paul, Ledson Martin J, Walshaw Martin J
The Cardiothoracic Centre, Liverpool, UK.
J Cyst Fibros. 2005 Sep;4(3):197-201. doi: 10.1016/j.jcf.2005.05.017.
Although acute renal failure has been described in children with CF in relation to intravenous aminoglycoside use, there are no reports in the adult CF literature. We describe 8 cases of acute renal failure in adult CF patients, all occurring during the use of intravenous aminoglycosides for the treatment of pulmonary exacerbations with an epidemic multi-resistant Pseudomonas aeruginosa strain. Potential contributory factors are discussed. These cases demonstrate another complication of infection by epidemic Pseudomonas strains in CF, and confirm the need for effective segregation policies to prevent this.
虽然已有关于患有囊性纤维化（CF）的儿童因使用静脉注射氨基糖苷类药物而出现急性肾衰竭的描述，但成人CF文献中尚无相关报道。我们描述了8例成年CF患者的急性肾衰竭病例，均发生在使用静脉注射氨基糖苷类药物治疗由一株具有流行多重耐药性的铜绿假单胞菌引起的肺部加重期时。文中讨论了可能的促成因素。这些病例证明了CF患者感染流行假单胞菌菌株的另一种并发症，并证实了需要有效的隔离政策来预防这种情况。
