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[不宁腿综合征:医疗实践中的治疗可能性]

[Restless legs syndrome: therapeutic possibilities in the medical practice].

作者信息

Bachmann C G, Trenkwalder C

机构信息

Abteilung Klinische Neurophysiologie, Klinikum der Universität Göttingen.

出版信息

MMW Fortschr Med. 2005 May 17;147 Spec No 2:44-7.

Abstract

The diagnosis of restless legs syndrome is made on the basis of the clinical symptoms and, if applicable, complemented with a polysomnography. This is followed by neurophysiological examinations and laboratory diagnostics and permits a differentiation between idiopathic and secondary RLS. The therapy depends upon the form and severity of the disease. For secondary RLS, the primary disease must be treated or the symptom-inducing medication must be discontinued. An idiopathic RLS is treated with drugs. Primarily, L-dopa/benserazide and dopaminergic agonists are used, but opioids and anticonvulsants are also successful.

摘要

不宁腿综合征的诊断基于临床症状,如有必要,可辅以多导睡眠图检查。随后进行神经生理学检查和实验室诊断,以区分特发性和继发性不宁腿综合征。治疗方法取决于疾病的类型和严重程度。对于继发性不宁腿综合征,必须治疗原发性疾病或停用引起症状的药物。特发性不宁腿综合征则采用药物治疗。主要使用左旋多巴/苄丝肼和多巴胺能激动剂,但阿片类药物和抗惊厥药物也有疗效。

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