Cánovas L, Morillas P, Castro M, García B, Souto A, Calvo T
Servicio de Anestesiología, Reanimación y Terapéutica del Dolor. Complexo Hospitalario Ourense.
Rev Esp Anestesiol Reanim. 2005 May;52(5):263-6.
To assess the effectiveness of continuous intrathecal analgesia as prophylaxis for postdural puncture headache (PDPH) and for analgesia during labor in 12 patients who suffered accidental dural puncture.
A total of 920 patients who received spinal analgesia during labor were enrolled. Group A (no accidental dural puncture) received a single dose of 10 mL of 0.2% ropivacaine, and 5 minutes later continuous epidural infusion of 0.125% ropivacaine and 3 micromg mL(-1) was started at a rate of a 5 mL h(-1); a 5 mL bolus dose was allowed every 20 minutes if needed. In patients who suffered accidental dural puncture (Group B) we inserted an intrathecal catheter to administer an initial dose of 3 mL of 0.2% ropivacaine and the same analgesic mixture at the same dose as was administered in Group A. Patient characteristics, analgesic efficacy, duration of labor and delivery, motor blockade, analgesic volume, and incidence of PDPH were recorded. The Student t test was used for statistical comparisons.
No significant differences in duration of labor and delivery, analgesic efficacy, or motor blockade were observed. The incidence of PDPH was 16.6% in Group B and 0.33% in Group A. The patients in Group B required more additional bolus doses: 10 (SD, 2) in Group B and 3 (1.25) in Group A (P<0.01).
Continuous intrathecal analgesia after accidental dural puncture was a safe way to provide analgesia during labor and to reduce the expected incidence of PDPH.
评估连续鞘内镇痛对12例意外硬膜穿破患者预防硬膜穿破后头痛(PDPH)及分娩镇痛的效果。
共纳入920例分娩时接受脊髓镇痛的患者。A组(无意外硬膜穿破)给予单次剂量10 mL的0.2%罗哌卡因,5分钟后开始以5 mL/h的速率持续硬膜外输注0.125%罗哌卡因和3μg/mL,必要时每20分钟可给予5 mL推注剂量。对于意外硬膜穿破的患者(B组),插入鞘内导管给予初始剂量3 mL的0.2%罗哌卡因,并给予与A组相同剂量的镇痛合剂。记录患者特征、镇痛效果、分娩持续时间、运动阻滞、镇痛药物用量及PDPH发生率。采用Student t检验进行统计学比较。
分娩持续时间、镇痛效果或运动阻滞方面未观察到显著差异。B组PDPH发生率为16.6%,A组为0.33%。B组患者需要更多额外推注剂量:B组为10(标准差,2)次,A组为3(1.25)次(P<0.01)。
意外硬膜穿破后连续鞘内镇痛是分娩期间提供镇痛及降低预期PDPH发生率的一种安全方法。