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[冠状动脉造影正常的急性心肌梗死:一项46例的描述性研究]

[Acute myocardial infarction with normal coronary angiography: a 46-cases descriptive study].

作者信息

Ben Ameur Youssef, Dekhil Ibtissem, Baraket Fériel, Terras Mouna, Longo Selma, Kraiem Sondos, Slimane Mohamed Lotfi

机构信息

Hôpital Habib Thameur, Service de cardiologie, Montfleury, Tunis, Tunisie.

出版信息

Tunis Med. 2005 Feb;83(2):98-102.

Abstract

This a retrospective study on 46 patients conducted over a 9-year period. These patients had an acute myocardial infarctus (AMI) confirmed wilth changes on the electrocardiogram and raised cardiac enzymes. However, the subsequent coronary angiography showed normal in all these patients. The purpose of our study is to assess epidemiologic, clinical, pronostic and therapeutic features of AMI with angiographically normal coronary arteries and compare the results obtained with those of AMI with coronary artery disease. AMI with angiographically normal coronary arteries is a first coronary event in young patients (mean age 47.7 years) having few coronary risk factors (54.3% have only one risk factor) mainly smoking (73.9%). The anterior location is prevalent. The patients with AMI and angiographically normal coronary arteries have a better prognosis than those with coronary artery stenosis. Indeed, their left ventricular function is unaltered (mean ejection fraction 48.7%). Hypokinesis is the most frequent abnormality of wall motion noticed. The patients' post infarction course is bengin when the coronary arteries are angiographically normal. The incidence of hemodynamic complications and ischemic recurrences are lower than in AMI with coronary stenosis. The choice treatment remains fibrinolysis.

摘要

这是一项对46例患者进行的为期9年的回顾性研究。这些患者经心电图改变及心肌酶升高确诊为急性心肌梗死(AMI)。然而,随后的冠状动脉造影显示所有这些患者的冠状动脉均正常。我们研究的目的是评估冠状动脉造影正常的AMI的流行病学、临床、预后和治疗特征,并将所得结果与冠状动脉疾病所致AMI的结果进行比较。冠状动脉造影正常的AMI是年轻患者(平均年龄47.7岁)的首次冠状动脉事件,这些患者几乎没有冠状动脉危险因素(54.3%仅有一个危险因素),主要是吸烟(73.9%)。病变以前壁为主。冠状动脉造影正常的AMI患者的预后优于冠状动脉狭窄患者。事实上,他们的左心室功能未改变(平均射血分数48.7%)。运动减弱是最常见的室壁运动异常。当冠状动脉造影正常时,患者的梗死后病程较好。血流动力学并发症和缺血复发的发生率低于冠状动脉狭窄所致的AMI。首选治疗仍然是溶栓治疗。

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