Fisberg Mauro, de Oliveira Cecilia Lacroix, de Pádua Cintra Isa, Losso Gabriela, Bueno Milena Baptista, Rhein Samantha Ottani, Maximino Priscila
Adolescent Center Federal University of Sao Paulo and Sao Marcos University- Brazil.
Arch Latinoam Nutr. 2004 Dec;54(4):402-7.
Recent studies using balanced hypocaloric diets with food substitutes in some meals, have presented positive results. There are no studies with the Brazilian population on the efficacy of using food substitute, together with a hypocaloric diet. Main objective of this study was to verify the effects of a hypocaloric diet using food substitutes as meal replacement on the body weight, lipid profile, and glucose and insulin plasma levels. Seventy eight subjects of both genders were selected, 20-50 years old, and a body weight index between 25 kg/m2 and 35 kg/m2. The study lasted for six months and it was divided in 2 phases of three months each- mass reduction for 3 months and 3 months for maintenance. The sample was randomly divided in two groups: Group A (control- 3 months of general nutritional and physical orientation followed by 3 months with 1 meal replacement) and Group B (intervention- 2 meals replacement a day plus nutritional and physical orientation for 3 months followed by 3 months with 1 meal replacement). Anthropometric measurements, percent body fat (%BF), biochemical profile and intake survey were performed at moments 0, 3 and 6 months. Both groups showed a significant decrease in %BF, weight, and consequently in their BMI, in the third and sixth month of follow up. However, weight loss in group B was higher than in group A. At the end of the treatment, 0 and 25.0% of the patients of the group A and B, respectively, presented a weight loss higher than 10% of the initial weight. Comparing the triglycerides, LDL-cholesterol and glucose levels, between the beginning and after the three and six months of treatment, there was a significant reduction in the individuals only in group B. In conclusion, the use of food substitutes as meal replacement, together with a balanced, hypocaloric diet, proved to be efficient in weight loss for Brazilian overweighed individuals.
近期一些研究采用在部分餐食中使用食物替代品的平衡低热量饮食，已呈现出积极成果。目前尚无针对巴西人群使用食物替代品并结合低低热量饮食效果的研究。本研究的主要目的是验证使用食物替代品作为餐食替代的低热量饮食对体重、血脂谱以及血糖和胰岛素血浆水平的影响。选取了78名年龄在20至50岁、体重指数在25kg/m²至35kg/m²之间的男女受试者。研究持续六个月，分为两个阶段，每个阶段三个月——前三个月减重，后三个月维持。样本被随机分为两组：A组（对照组——先进行三个月的一般营养和身体指导，随后三个月进行一次餐食替代）和B组（干预组——每天进行两次餐食替代并结合营养和身体指导三个月，随后三个月进行一次餐食替代）。在第0、3和6个月时进行人体测量、体脂百分比（%BF）、生化指标分析和摄入量调查。在随访的第三个月和第六个月，两组的%BF、体重以及相应的BMI均显著下降。然而，B组的体重减轻幅度高于A组。治疗结束时，A组和B组分别有0和25.0%的患者体重减轻超过初始体重的10%。比较治疗开始时以及治疗三个月和六个月后的甘油三酯、低密度脂蛋白胆固醇和血糖水平，仅B组个体有显著降低。总之，对于巴西超重个体，使用食物替代品作为餐食替代并结合平衡的低热量饮食被证明在减肥方面是有效的。
