Cheng F W T, Ng P C, Chiu W K, Chu W C W, Li A M, Lo K L, Hon E K L, Nelson E A S, Leung T F, Ng W H, Wong E, Ip P, Fok T F
Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong.
Arch Dis Child. 2005 Jul;90(7):747-9. doi: 10.1136/adc.2004.063446.
The clinical, laboratory, and radiological features at presentation of 16 children (<12 years) with severe acute respiratory syndrome (SARS) and pneumonia were compared with 32 age matched patients with community acquired pneumonia for determination of predictive factors that could allow early differentiation of the two conditions. A definitive contact history was the most important predictor for SARS. Raised serum lactate dehydrogenase concentration in the presence of low neutrophil count and serum creatine phosphokinase level at presentation also indicated an increased likelihood of SARS-coronavirus infection in young children.
将16名患有严重急性呼吸综合征(SARS)和肺炎的12岁以下儿童的临床表现、实验室检查及影像学特征与32名年龄匹配的社区获得性肺炎患者进行比较,以确定能够早期区分这两种疾病的预测因素。明确的接触史是SARS最重要的预测因素。就诊时血清乳酸脱氢酶浓度升高且中性粒细胞计数低以及血清肌酸磷酸激酶水平升高也表明幼儿感染SARS冠状病毒的可能性增加。