Gong Q Y, Zhu H Y, Zheng G L, Wang Y, Yuan C M, Cheng L, Wu P H, Lu L X, Huang Q L, Zhang X L
Department of Radiology, Affiliated Hospital of Zunyi Medical College.
Chin Med J (Engl). 1992 Feb;105(2):135-8.
The possibility of T2 values in the differentiation of local recurrence and irradiation fibrosis was studied prospectively in 36 patients with nasopharyngeal carcinoma (NPC) after radiotherapy. All the patients had a soft-tissue mass in the nasopharynx demonstrated by CT. Fourteen patients had tumor recurrence, 20 radiation fibrosis, 1 postradiation edema, and 1 inflammatory change. The control group consisted of 8 patients with untreated NPC. It was found that T2 was longer in patients with tumor than in patients with radiation fibrosis. We conclude that MRI may be used as a noninvasive method for differentiating radiation fibrosis from local recurrent NPC, but the prolonged T2 value of tumor is not specific and may be seen in radiation edema and infection.
我们前瞻性地研究了T2值在鼻咽癌（NPC）放疗后局部复发与放射性纤维化鉴别诊断中的可能性，共纳入36例患者。所有患者经CT检查均显示鼻咽部有软组织肿块。其中14例为肿瘤复发，20例为放射性纤维化，1例为放疗后水肿，1例为炎症改变。对照组由8例未经治疗的NPC患者组成。结果发现，肿瘤患者的T2值长于放射性纤维化患者。我们得出结论，MRI可作为一种无创方法用于鉴别放射性纤维化与NPC局部复发，但肿瘤T2值延长并不具有特异性，在放射性水肿和感染中也可能出现。
