Eagan T M L, Brøgger J C, Eide G E, Bakke P S
Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
Int J Tuberc Lung Dis. 2005 Jun;9(6):603-12.
In recent years, several new studies have estimated the incidence of adult asthma. These studies vary in design and quality. The current paper summarises the findings of major population studies in the adult incidence of asthma. The pooled estimate of the adult incidence of asthma was 4.6 per 1000 person-years in women and 3.6 per 1000 person-years in men. The estimate among only general population cohort studies was higher, respectively 5.9 and 4.4 per 1000 person-years in women and men. The adult incidence of asthma was slightly higher in women than men. In the few studies that allowed the incidence of asthma to be estimated among those aged >50 years, there was a trend towards a higher incidence with age. It is thought likely that this is at least partly explained by misclassification with COPD. However, the current findings from these studies may imply that the incidence of asthma in the elderly has previously been under-estimated. Finally, the review shows that estimates of adult asthma incidence have tended to be higher in later studies, implying a rise in asthma incidence in adults within the timeframe of observation.
近年来,多项新研究对成人哮喘的发病率进行了估算。这些研究在设计和质量上各有不同。本文总结了关于成人哮喘发病率的主要人群研究结果。哮喘在女性中的合并发病率为每1000人年4.6例,在男性中为每1000人年3.6例。仅在普通人群队列研究中的估算值更高,女性和男性分别为每1000人年5.9例和4.4例。哮喘在女性中的成人发病率略高于男性。在少数能够估算50岁以上人群哮喘发病率的研究中,发病率有随年龄增长而升高的趋势。据认为,这至少部分可由慢性阻塞性肺疾病(COPD)的误诊来解释。然而,这些研究目前的结果可能意味着老年人哮喘的发病率此前被低估了。最后,该综述表明,在后期研究中成人哮喘发病率的估算值往往更高,这意味着在观察期内成人哮喘发病率有所上升。