Jinno Hiromitsu, Ikeda Tadashi, Asaga Sota, Muto Takeshi, Kitagawa Yuko, Fujii Hirofumi, Mukai Makio, Kitajima Masaki
Department of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160, Japan.
Am J Surg. 2005 Jul;190(1):51-4. doi: 10.1016/j.amjsurg.2004.08.067.
Increasing age of breast cancer patients was reported to cause not only failure of sentinel lymph node (SLN) identification but also false negative results.
A retrospective review was conducted of breast cancer patients who underwent sentinel lymph node biopsy (SLNB) using small-sized technetium-99m-labeled tin colloid (particle size: 200-400 nm in diameter). A comparison between 82 patients who were less than 60 years and 40 patients who were > or =60 years of age was performed to evaluate the efficacy of SLNB using the small-sized tin colloid in older patients.
One hundred twenty-two clinically node-negative breast cancer patients underwent SLNB. Apart from age, there were no statistically significant differences between the younger patients and the older patients in terms of the clinicopathologic characteristics. Successful mapping rates, false negative rates, and accuracy were comparable between the 2 groups.
SLNB using the small-sized tin colloid was not affected by increasing age.
据报道，乳腺癌患者年龄的增加不仅会导致前哨淋巴结（SLN）识别失败，还会导致假阴性结果。
对使用小尺寸99m锝标记锡胶体（粒径：直径200 - 400 nm）进行前哨淋巴结活检（SLNB）的乳腺癌患者进行回顾性研究。比较82例年龄小于60岁的患者和40例年龄大于或等于60岁的患者，以评估在老年患者中使用小尺寸锡胶体进行SLNB的疗效。
122例临床淋巴结阴性的乳腺癌患者接受了SLNB。除年龄外，年轻患者和老年患者在临床病理特征方面无统计学显著差异。两组的成功定位率、假阴性率和准确率相当。
使用小尺寸锡胶体进行SLNB不受年龄增加的影响。
