Bongrand P, Capo C, Benoliel A M, Depieds R
C R Seances Soc Biol Fil. 1979;173(2):231-46.
Macrophages are involved in many immunological functions such as phagocytosis, cytotoxicity, antigen binding and cooperation with lymphocytes. The triggering of those functions involves membrane receptors. Several receptors species are well characterized, but some phenomena can be accounted for only if macrophages are endowed with nonspecific adhesive structures. A study of the effect of various physical or chemical factors on the binding of several particle species by rat peritoneal macrophages allowed us to classify nonspecific receptors and discuss the mechanisms involved in some types of cellular interaction.
巨噬细胞参与许多免疫功能,如吞噬作用、细胞毒性、抗原结合以及与淋巴细胞的协作。这些功能的触发涉及膜受体。几种受体类型已得到充分表征,但有些现象只有在巨噬细胞具有非特异性黏附结构时才能得到解释。一项关于各种物理或化学因素对大鼠腹腔巨噬细胞结合几种颗粒类型的影响的研究,使我们能够对非特异性受体进行分类,并探讨某些类型细胞相互作用所涉及的机制。