Abreu-Goodger Cei, Merino Enrique
Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, 62210 Morelos, México.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W690-2. doi: 10.1093/nar/gki445.
We present RibEx (riboswitch explorer), a web server capable of searching any sequence for known riboswitches as well as other predicted, but highly conserved, bacterial regulatory elements. It allows the visual inspection of the identified motifs in relation to attenuators and open reading frames (ORFs). Any of the ORF's or regulatory elements' sequence can be obtained with a click and submitted to NCBI's BLAST. Alternatively, the genome context of all other genes regulated by the same element can be explored with our genome context tool (GeConT). RibEx is available at http://www.ibt.unam.mx/biocomputo/ribex.html.
我们展示了RibEx(核糖开关探索器),这是一个网络服务器,能够在任何序列中搜索已知的核糖开关以及其他预测的但高度保守的细菌调控元件。它允许直观检查与弱化子和开放阅读框(ORF)相关的已识别基序。只需点击一下,即可获取任何ORF或调控元件的序列,并提交到NCBI的BLAST。或者,可以使用我们的基因组上下文工具(GeConT)探索由同一元件调控的所有其他基因的基因组上下文。可通过http://www.ibt.unam.mx/biocomputo/ribex.html访问RibEx。