Tromas Christophe, Eaton Peter, Mimault Jean, Rojo Javier, Penadés Soledad
Laboratoire de Métallurgie Physique, SP2MI, Bld Marie et Pierre Curie, BP 30179, 86962 Futuroscope Cedex, France.
Langmuir. 2005 Jul 5;21(14):6142-4. doi: 10.1021/la050051f.
Thiolated self-assembled monolayers of carbohydrates may serve as useful polyvalent tools to mimic the organized presentation of such molecules at the cell surface. SAMs presenting the disaccharide maltose as a neoglycoconjugate were produced, and the structure was studied by high resolution atomic force microscopy. The molecules form highly ordered structures on a gold (111) surface, with lattice parameters determined by the linker moiety rather than the headgroup.
碳水化合物的硫醇化自组装单分子层可作为有用的多价工具，用于模拟此类分子在细胞表面的有序呈现。制备了呈现二糖麦芽糖作为新糖缀合物的自组装单分子层，并通过高分辨率原子力显微镜研究了其结构。这些分子在金（111）表面形成高度有序的结构，其晶格参数由连接部分而非头基决定。
