免疫球蛋白G介导的肠易激综合征食物不耐受：一种真实存在的现象还是一种附带现象？

IgG-mediated food intolerance in irritable bowel syndrome: a real phenomenon or an epiphenomenom?

作者信息

Shanahan Fergus, Whorwell Peter J

出版信息

Am J Gastroenterol. 2005 Jul;100(7):1558-9. doi: 10.1111/j.1572-0241.2005.50009.x.

DOI:10.1111/j.1572-0241.2005.50009.x

Abstract

Abnormal reactions to food probably contribute to the complex pathophysiology of irritable bowel syndrome, but the mechanisms involved remain unclear. Following the recent identification of subtle mucosal inflammation in at least some patients with the disorder, perhaps now is the time to revisit some of the immunological reactions to dietary antigens that, in the past, have been dismissed as irrelevant.

摘要

对食物的异常反应可能导致肠易激综合征复杂的病理生理学，但其中涉及的机制仍不清楚。随着最近在至少部分该疾病患者中发现了细微的黏膜炎症，或许现在是时候重新审视过去被认为无关紧要的一些对饮食抗原的免疫反应了。