Honkalampi Kirsi, Hintikka Jukka, Haatainen Kaisa, Koivumaa-Honkanen Heli, Tanskanen Antti, Viinamäki Heimo
Department of Psychiatry, Research and Development Unit, Kuopio University Hospital, P.O. Box 1777, FIN-70211, Kuopio, Finland.
Aust N Z J Psychiatry. 2005 Jul;39(7):627-32. doi: 10.1080/j.1440-1614.2005.01636.x.
The aim of this study was to simultaneously test adverse background factors, namely adverse childhood experiences (ACEs), stressful life events and prior depressive symptoms, for their ability to predict recovery and non-recovery from depression in women among the general population.
A stratified random sample of women (n = 835) from the general population was collected at baseline in 1999. Depression (Beck Depression Inventory, BDI-21), ACEs and background factors were assessed by postal questionnaire at baseline. Two years later, stressful life events during the study phase, social support, use of health services and current depression (BDI > or = 13) were similarly assessed.
Adverse childhood experiences were common among depressed women and these past experiences together with the use of health services were associated with recovery from depression. Financial difficulties and a poor subjective health status associated with non-recovery and current stressful life events increased the likelihood of depression on follow-up. Furthermore, the important variables explaining depression on follow-up were the quality of social support and the existence of prior depressive symptoms at baseline.
Our results suggest that women's current depression especially associates with stressful life events, insufficient social support, poor subjective health and financial difficulties. It seems possible that past adverse experiences predispose women to depression, but current stressful events actualize these symptoms. In addition, use of health services are associated with recovery in women who had ACEs.
本研究旨在同时检验不良背景因素,即儿童期不良经历(ACEs)、应激性生活事件和既往抑郁症状,预测普通人群中女性抑郁症康复和未康复情况的能力。
1999年在基线时收集了来自普通人群的女性分层随机样本(n = 835)。在基线时通过邮寄问卷评估抑郁症(贝克抑郁量表,BDI - 21)、ACEs和背景因素。两年后,同样评估研究阶段的应激性生活事件、社会支持、医疗服务利用情况和当前抑郁症(BDI≥13)。
儿童期不良经历在抑郁女性中很常见,这些既往经历连同医疗服务利用情况与抑郁症康复相关。经济困难和较差的主观健康状况与未康复相关,当前的应激性生活事件增加了随访时患抑郁症的可能性。此外,解释随访时抑郁症的重要变量是社会支持质量和基线时既往抑郁症状的存在情况。
我们的结果表明,女性当前的抑郁症尤其与应激性生活事件、社会支持不足、主观健康状况差和经济困难相关。过去的不良经历可能使女性易患抑郁症,但当前的应激事件会使这些症状显现出来。此外,医疗服务利用情况与有ACEs的女性康复相关。