Coombs V J, Black L, Townsend S N
Crit Care Nurs Clin North Am. 1992 Jun;4(2):339-46.
Oxygen-free radical production and reperfusion injury are complex mechanisms. New and improved methods for maximizing the benefits of reperfusion while minimizing reperfusion injury are on the horizon in the 1990s. Critical care nurses play a crucial role in the assessment, planning, and intervention of patients experiencing the deleterious effects of free radicals and reperfusion injury. Thus, a sound knowledge base in the pathophysiology of reperfusion injury, the detrimental effects of free radicals, and the potential benefits of free-radical scavengers is essential.
氧自由基的产生和再灌注损伤是复杂的机制。在20世纪90年代，能够在使再灌注益处最大化的同时将再灌注损伤最小化的新的和改进的方法即将出现。重症护理护士在评估、规划以及对遭受自由基和再灌注损伤有害影响的患者进行干预方面发挥着关键作用。因此，具备关于再灌注损伤病理生理学、自由基的有害影响以及自由基清除剂潜在益处的扎实知识基础至关重要。
