Ruiz Montes F, Reñé Espinet J M, Rubio Caballero M
Servicio de Medicina Interna, Facultad de Medicina, Hospital Arnau de Vilanova, Lérida.
Rev Esp Enferm Dig. 1992 Apr;81(4):270-9.
We review the Spanish literature on Eosinophilic Gastroenteritis. The data are compared with those of several foreign series. Abdominal pain, vomiting, diarrhea, and abdominal distension due to ascites were the most frequent clinical manifestations. In our country most cases had ascites. A history of allergy was reported by less than on half of patients. Peripheral eosinophilia with otherwise normal laboratory findings is the rule. However, peripheral eosinophilia was not essential for diagnosis, since it was absent in one quarter of patients. Small intestine barium studies were abnormal almost always, but the findings were not specific. The diagnosis is based on the endoscopic and/or peroral gastrointestinal biopsy. However, a false negative diagnosis can occur, since the disease can take up a patchy distribution, or a more profound involvement of the gastrointestinal layers without mucosal disease. The treatment of choice is corticosteroids, with a spectacular therapeutic response. Complete studies with biopsies taken at multiple levels of the gastrointestinal tract, are necessary to ascertain the extent and depth of the disease. The etiology is unknown, and although allergy causes can be elicited in some cases, they are absent in the majority of them. We encounter no essential differences in the eosinophilic gastroenteritis characteristics in our country in relation to other countries.
我们回顾了关于嗜酸性粒细胞性胃肠炎的西班牙文文献。将这些数据与几个国外系列的数据进行了比较。腹痛、呕吐、腹泻以及腹水导致的腹胀是最常见的临床表现。在我国,大多数病例有腹水。不到一半的患者报告有过敏史。外周血嗜酸性粒细胞增多而其他实验室检查结果正常是常见情况。然而,外周血嗜酸性粒细胞增多并非诊断所必需,因为四分之一的患者没有该表现。小肠钡剂造影几乎总是异常,但结果不具特异性。诊断基于内镜检查和/或经口胃肠道活检。然而,可能会出现假阴性诊断,因为该病可能呈斑片状分布,或者胃肠道各层受累更严重而无黏膜病变。首选治疗是使用皮质类固醇,治疗反应显著。进行完整的研究,在胃肠道多个层面取活检,对于确定疾病的范围和深度是必要的。病因不明,虽然在某些情况下可引发过敏原因,但大多数病例并非如此。我国嗜酸性粒细胞性胃肠炎的特征与其他国家相比没有本质差异。