Andrzejak Ryszard, Poreba Małgorzata, Poreba Rafał, Beck Bogusław, Steinmetz-Beck Aleksandra, Kuliczkowski Kazimierz
Z Katedry i Kliniki Chorób Wewnetrznych, Zawodowych i Nadciśnienia Tetniczego.
Med Pr. 2005;56(1):35-9.
Pneumoconiosis is the most common occupational disease of the respiratory system. The aim of this paper is presentation of case of pneumoconiosis coexisting with myelodysplastic syndrome in a former coal miner occupationally exposed to coal dust. In a mineral coal miner, aged 56 year, with a 15-year duration of work underneath, suffering from pneumoconiosis, pancytopenia was detected. He was admitted to the hospital, where myelodysplastic syndrome was diagnosed. The patient's condition was gradually worsening, even though chemotherapy was applied, he died from thrombocytopenia manifested by bleeding from the digestive tract in a relatively short time since diagnosis. The presented case seems to be interesting not only in view of possible development of pneumoconiosis as a result of occupational exposure to coal dust, typical in this case, but also in view of the occurrence of clonal disease of blood several years after cessation of exposure.
尘肺病是最常见的呼吸系统职业病。本文旨在介绍一名曾职业性接触煤尘的煤矿工人同时患有尘肺病和骨髓增生异常综合征的病例。一名56岁的煤矿工人,井下工作15年,患有尘肺病,检测发现全血细胞减少。他被收治入院,随后被诊断为骨髓增生异常综合征。尽管进行了化疗,但患者病情逐渐恶化,自诊断后较短时间内便死于因消化道出血所致的血小板减少症。该病例不仅因职业性接触煤尘(此病例中的典型情况)可能导致尘肺病的发生而引人关注,还因接触停止数年之后出现血液克隆性疾病而备受关注。