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[晶状体厚度与全基质角膜厚度的关系精度。板层微型角膜刀的实验结果]

[Precision of lenticular thickness in relation to full stroma corneal thickness. Experimental results with the lamellar microkeratome].

作者信息

Wilmes C, Draeger J, Kohlhaas M

机构信息

Universitäts-Augenklinik Hamburg, Eppendorf.

出版信息

Ophthalmologe. 1992 Apr;89(2):147-50.

PMID:1600323
Abstract

In this study 150 pig corneas and 20 human corneas were dissected with an automatic rotating microkeratome for lamellar grafting. The cornea thickness varied between 0.507 mm and 0.829 with an average 0.66 mm. The aim of this investigation was to show the influence of corneal thickness, the chosen diameter and spacing on the precision of cutting lenticles. We did ten series: the pig corneas were dissected at three different intervals of 0.15, 0.25, 0.35 mm and diameters of 9 and 6mm. The human corneas were cut at intervals of 0.4 mm and 0.25 mm and with diameter of 9 and 7 mm. Although the pig corneas were fresh, the intraocular pressure was too low. It was raised with an injection of physiological salt solution to a predefined level. The rotating speed of the trephine blade, the speed of blade advancement and lubrication fluid were kept constant. Ultrasound pachymetry was performed on the center of the corneas before cutting had on the lenticles afterward. We showed that a thick corneal diameter had a negative influence, i.e., the greater the diameter, the lesser the precision; the same was true for the corneal thickness. On the other hand, the intervals had just the opposite effect: the closer they were, the better the correlation. The human eye results were different in quantity but not in tendency, with less striking effects. The average variation for pig corneas was 22% and for human eyes 8%. The best results were received with a large interval, a small diameter, and a normal corneal thickness in human eyes.

摘要

在本研究中,使用自动旋转微型角膜刀对150个猪角膜和20个人角膜进行剖切,用于板层移植。角膜厚度在0.507毫米至0.829毫米之间变化,平均为0.66毫米。本研究的目的是展示角膜厚度、所选直径和间距对剖切透镜体精度的影响。我们进行了十组实验:对猪角膜以0.15毫米、0.25毫米、0.35毫米这三种不同间距以及9毫米和6毫米的直径进行剖切。对人角膜以0.4毫米和0.25毫米的间距以及9毫米和7毫米的直径进行剖切。尽管猪角膜是新鲜的,但眼内压过低。通过注射生理盐水将其提升至预定水平。环钻刀片的转速、刀片推进速度和润滑液保持恒定。在剖切角膜前对角膜中心进行超声测厚,并在剖切透镜体后再次测量。我们发现角膜直径较大有负面影响,即直径越大,精度越低;角膜厚度也是如此。另一方面,间距则有相反的效果:间距越小,相关性越好。人眼的结果在数量上有所不同,但趋势相同,影响较小。猪角膜的平均变异为22%,人眼为8%。人眼中,大间距、小直径和正常角膜厚度能获得最佳结果。

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