Agarwal Avinash, Maglinte Dean D T, Goggins William C, Milgrom Martin L, Pescovitz Mark D, Fridell Jonathan A
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Transplantation. 2005 Jul 15;80(1):149-52. doi: 10.1097/01.tp.0000162983.59042.e9.
Although complications involving leaking at the enteric anastomosis site, graft thrombosis, and intraabdominal abscess formation have been well documented after pancreas transplantation, the occurrence of small bowel obstruction in this setting has received scant attention. Although uncommon, intestinal obstruction after pancreas transplantation may have atypical etiologies. In this article, we will review three unusual cases of intestinal obstruction in pancreas transplant recipients. The value of computed tomographic (CT) enteroclysis in equivocal situations in the diagnosis of the obstruction is emphasized.
In this study, we reviewed the posttransplant course of all pancreas transplants performed between July 1, 2002 and June 1, 2004. We specifically focused on all patients that required reexploration for suspected small bowel obstruction at any time after transplantation.
A total of 65 pancreas transplants were performed between July 1, 2002 and June 1, 2004. Pancreas graft survival was 97%, and patient survival was 98.5%. Five (7.7%) patients presented with mechanical small bowel obstruction, three of which were secondary to internal herniation of small intestine through a defect posterior to the pancreas allograft. All patients recovered well postsurgically.
Small bowel obstruction is an uncommon complication after pancreas transplantation. CT enteroclysis in the evaluation of small bowel obstruction may assist the patient care decision-making process by providing information on the location and severity of the obstruction in the clinical situation where conventional abdominal CT and radiography are equivocal. Prompt detection of small bowel obstruction with early surgical intervention can minimize complications and preserve allograft function.
尽管胰腺移植后肠吻合口漏、移植血管血栓形成和腹腔内脓肿形成等并发症已有充分记录,但在这种情况下小肠梗阻的发生却很少受到关注。虽然不常见,但胰腺移植后的肠梗阻可能有非典型病因。在本文中,我们将回顾三例胰腺移植受者发生肠梗阻的不寻常病例。强调了计算机断层扫描(CT)小肠灌肠造影在诊断不明确情况下对肠梗阻的价值。
在本研究中,我们回顾了2002年7月1日至2004年6月1日期间进行的所有胰腺移植的术后过程。我们特别关注了所有在移植后任何时间因疑似小肠梗阻而需要再次手术探查的患者。
2002年7月1日至2004年6月1日期间共进行了65例胰腺移植。胰腺移植存活率为97%,患者存活率为98.5%。5例(7.7%)患者出现机械性小肠梗阻,其中3例继发于小肠通过胰腺移植后缺损处的内疝。所有患者术后恢复良好。
小肠梗阻是胰腺移植后一种不常见的并发症。在传统腹部CT和X线检查结果不明确的临床情况下,CT小肠灌肠造影在评估小肠梗阻时可通过提供梗阻部位和严重程度的信息来辅助患者的治疗决策过程。早期手术干预及时发现小肠梗阻可将并发症降至最低并保留移植胰腺功能。