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替代指标的替代指标:高血压与24小时血压监测的故事

Surrogates of surrogates: the story of hypertension and 24 h blood pressure monitoring.

作者信息

Grewal Jasmine, Lonn Eva

机构信息

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

出版信息

Can J Cardiol. 2005 Jun;21(8):639-42.

PMID:16003447
Abstract

Ambulatory blood pressure (ABP) monitoring is emerging as a useful tool in the diagnosis and management of hypertension. It is particularly useful in certain settings, such as the identification of patients with 'white coat hypertension', the evaluation of patients with unexplained symptoms or end-organ damage, the study of circadian variations in BP and the management of patients with refractory hypertension (as assessed by office BP measurements), and as a guide to antihypertensive treatment. Recent data suggest that ABP monitoring may be superior to office BP measurements in the assessment of risk of hypertensive end-organ damage and clinical events. However, further evidence that the use of ABP monitoring can improve patients' clinical outcomes is needed and would make the use of this promising technique more compelling and more widely accepted.

摘要

动态血压监测正逐渐成为高血压诊断和管理中的一项有用工具。它在某些情况下尤其有用,比如识别“白大衣高血压”患者、评估有不明症状或靶器官损害的患者、研究血压的昼夜变化以及难治性高血压患者的管理(通过诊室血压测量评估),并作为抗高血压治疗的指导。近期数据表明,在评估高血压靶器官损害风险和临床事件方面,动态血压监测可能优于诊室血压测量。然而,仍需要进一步证据证明使用动态血压监测能够改善患者的临床结局,这将使这项有前景的技术更具说服力且被更广泛地接受。

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