Horlitz M, Schley P, Shin D-I, Ghouzi A, Klein R M, Gülker H
Abt. für Elektrophysiologie und Rhythmologie, Herzzentrum Wuppertal, Kardiologie, HELIOS Klinikum Wuppertal, Universitätsklinikum der Universität Witten/Herdecke.
Dtsch Med Wochenschr. 2005 Jul 15;130(28-29):1683-8. doi: 10.1055/s-2005-871884.
The implantable cardioverter defibrillator (ICD) is the therapy of choice for patients with ventricular tachycardia (VT) after myocardial infarction. In some patients frequent ICD shocks occur, often resulting in clinical problems, if antiarrhythmic drugs insufficiently suppress them. Our aim was to describe electro-anatomical mapping and ablation techniques in patients with VTs, in which conventional strategy treatments have failed.
17 patients (69.5 +/- 8 years, 12 male) were included. During 3 months before ablation the number of ICD shocks was 21 +/- 8 (mean +/- SD). Using an electro-anatomical mapping system (CARTO), activation mapping was performed in 12 patients during hemodynamically tolerable, stable VT. In 5 cases with "non-mappable" VT only voltage mapping during sinus rhythm was obtained. The aim was to characterize the underlying scar tissue precisely in order to modify the substrate with an individual strategic linear lesion, thus preventing re-induction of VT.
Procedure time was 184 +/- 9 minutes, fluoroscopy time totalled 19 +/- 9 minutes. Lesion lines were established with 13 +/- 9 ablation pulses. In 15 patients (88 %) acute ablation of the VT was successful. During a follow-up of 8 +/- 7 months, 2 patients had a recurrence of the VT. Two patients developed a VT with a different morphology. In another case ventricular fibrillation occurred. No major complications were observed.
Electro-anatomical mapping combined with an individual linear ablation strategy is a safe and effective method to prevent symptomatic VT in patients after myocardial infarction.
植入式心脏复律除颤器(ICD)是心肌梗死后室性心动过速(VT)患者的首选治疗方法。在一些患者中,如果抗心律失常药物不能充分抑制VT,就会频繁发生ICD电击,常常导致临床问题。我们的目的是描述在传统策略治疗失败的VT患者中进行电解剖标测和消融技术。
纳入17例患者(年龄69.5±8岁,男性12例)。在消融前3个月期间,ICD电击次数为21±8次(均值±标准差)。使用电解剖标测系统(CARTO),在12例血流动力学可耐受的稳定VT患者中进行激动标测。在5例“无法标测”的VT患者中,仅在窦性心律时进行电压标测。目的是精确表征潜在的瘢痕组织,以便用个体化的策略性线性病变改变基质,从而防止VT的再次诱发。
手术时间为184±9分钟,透视时间总计19±9分钟。使用13±9次消融脉冲建立病变线。15例患者(88%)VT的急性消融成功。在8±7个月的随访期间,2例患者VT复发。2例患者出现形态不同的VT。在另一例中发生了心室颤动。未观察到重大并发症。
电解剖标测结合个体化线性消融策略是预防心肌梗死后患者症状性VT的一种安全有效的方法。