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[气肿性肾盂肾炎:诊断与治疗]

[Emphysematous pyelonephritis: diagnosis and treatment].

作者信息

Kaiser E, Fournier R

机构信息

Anesthésiste-réanimateur des Hôpitau des Armées, département d'anesthésie-réanimation, France.

出版信息

Ann Urol (Paris). 2005 Apr;39(2):49-60. doi: 10.1016/j.anuro.2005.04.001.

Abstract

Emphysematous pyelonephritis is a necrotizing kidney infection characterized by the presence of gas in renal parenchyma, collecting system or perinephric tissue. This rare affection occurs almost exclusively in patients with diabetes mellitus and is due to non-anaerobic gas-producing bacteria. This life-threatening condition leads to septic shock and multiple organ failure. Diagnosis is suspected when a pyelonephritis does not respond to correct treatment, especially with altered vital signs or a diabetic patient. Computed tomography scan permits visualization of the gas and a radiologic classification with a prognostic value. Current treatment modalities are based upon repeated clinical and scanographic evaluations. In addition to systematic antibiotic therapy, percutaneous drainage is probably the first therapeutic stage in the majority of cases, but should not delay emergent rescue nephrectomy if necessary.

摘要

气肿性肾盂肾炎是一种坏死性肾脏感染,其特征是肾实质、集合系统或肾周组织中存在气体。这种罕见的病症几乎仅发生于糖尿病患者,由非厌氧产气细菌引起。这种危及生命的病症会导致感染性休克和多器官功能衰竭。当肾盂肾炎对正确治疗无反应,尤其是生命体征改变或患者为糖尿病患者时,应怀疑该病。计算机断层扫描可显示气体,并进行具有预后价值的影像学分类。目前的治疗方式基于反复的临床和影像学评估。除了系统性抗生素治疗外,在大多数情况下,经皮引流可能是首要治疗阶段,但如有必要,不应延迟紧急抢救性肾切除术。

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