胆石症相关性肝炎中体液免疫和细胞免疫反应的各个方面。
Aspects of the humoral and cellular immune response in hepatitis associated with cholelithiasis.
作者信息
Bădescu Maria Elisabeta, Stancu Manuela, Pandele G I, Cotuţiu C, Amălinei Cornelia, Balan Raluca
机构信息
Gr.T. Popa University of Medicine and Pharmacy, Iaşi School of Medicine, Department of Pathology.
出版信息
Rev Med Chir Soc Med Nat Iasi. 2004 Oct-Dec;108(4):827-31.
AIM
To investigate the immunological reactions of the liver in various gall bladder disease.
METHODS
IgG, IgA and IgM were measured in the blood and bile of patients with cholecystectomy. Immunofluorescence and electron microscopy techniques were used.
RESULTS
The tests showed high blood values of immunoglobulins and their presence in the bile. The immunofluorescence was positive for IgG in the hepatic sinusoids. The electron microscopy showed aspects of "cellular cooperation".
CONCLUSIONS
On the basis of our results we can affirm that in cholelithiasis there exists an immune response to the persistent antigens, with the release of circulating immune complexes.
目的
研究肝脏在各种胆囊疾病中的免疫反应。
方法
对胆囊切除患者的血液和胆汁进行IgG、IgA和IgM检测。采用免疫荧光和电子显微镜技术。
结果
检测显示免疫球蛋白血液值升高且存在于胆汁中。肝血窦中IgG免疫荧光呈阳性。电子显微镜显示出“细胞协作”的特征。
结论
根据我们的结果，我们可以肯定，在胆石症中存在对持续抗原的免疫反应，并伴有循环免疫复合物的释放。
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