[A charge-deficient analogue of spermine with chelating properties].
作者信息
Khomutov A R, Grigorenko N A, Demin A V, Vepsalainen J, Casero R A, Woster P M
出版信息
Bioorg Khim. 2005 May-Jun;31(3):303-11. doi: 10.1007/s11171-005-0037-1.
PMID:16004389
Abstract
1,12-Diamino-3,6,9-triazadodecane, a new isosteric and charge-deficient analogue of spermine, is synthesized. Unlike spermine, the new analogue is an excellent chelator of Cu2+ ions. Possible applications of this compound for studying enzymes of polyamine metabolism and cellular functions of spermine are discussed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 3; see also http://www.maik.ru.
摘要
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