Khosravi Shahi P, del Castillo Rueda A
Servicios de Oncología Medica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
An Med Interna. 2005 Apr;22(4):185-7.
Histiocytic sarcoma is a rare neoplasm, and its aetiology is unknown. It is a malignant proliferation of neoplastic cells showing immunophenotypic and morphologic features similar to tissue histiocytes. The clinical course of histiocytic sarcoma is usually agressive. The signs and symptoms of histiocytic sarcoma are systemic symptoms (fever, weight loss), hepatosplenomegaly, adenopathies, intestinal obstruction, rash and pancytopenia. We present the case of a 75 years old woman, with fever, weight loss, anorexia, fatigue, splenomegaly and pancytopenia. Bone marrow examination showed the diagnosis of histiocytic sarcoma.
组织细胞肉瘤是一种罕见的肿瘤，其病因尚不清楚。它是一种肿瘤细胞的恶性增殖，表现出与组织细胞相似的免疫表型和形态学特征。组织细胞肉瘤的临床病程通常较为凶险。组织细胞肉瘤的体征和症状包括全身症状（发热、体重减轻）、肝脾肿大、淋巴结病、肠梗阻、皮疹和全血细胞减少。我们报告一例75岁女性患者，有发热、体重减轻、厌食、疲劳、脾肿大和全血细胞减少。骨髓检查确诊为组织细胞肉瘤。
