Lecuit Thomas
Laboratoire de Génétique et de Physiologie du Développement, UMR 6545, CNRS-Université de la Méditerrannée, Institut de Biologie du Développement de Marseille, France.
Curr Biol. 2005 Jul 12;15(13):R505-7. doi: 10.1016/j.cub.2005.06.028.
Cadherins control intercellular adhesion in epithelial cells. This property relies on the ability to recruit actin filaments at adherens junctions via beta-catenin and alpha-catenin. A recent study shows that Echinoid, a member of the immunoglobulin domain containing protein family, is a modulator of intercellular adhesion in Drosophila that controls cell sorting.
钙黏蛋白控制上皮细胞中的细胞间黏附。这一特性依赖于通过β-连环蛋白和α-连环蛋白在黏着连接处募集肌动蛋白丝的能力。最近一项研究表明，类海胆蛋白（免疫球蛋白结构域包含蛋白家族的成员）是果蝇中细胞间黏附的调节剂，可控制细胞分选。
