Wang Wei-Hua, Sun Xiao-Fang
In Vitro Fertilization Laboratory, Tomball Regional Hospital, TX 77375, USA.
Hum Reprod. 2005 Nov;20(11):2987-9. doi: 10.1093/humrep/dei197. Epub 2005 Jul 8.
Human embryonic stem (hES) cells have the potential to differentiate into any desired cells and to be used in cell replacement therapies for some diseases. However, existing hES cell lines would not be suitable for the therapies as they are contaminated with other biological products. In order to produce the safest hES cell lines for therapeutic purposes, all steps for the establishment of hES cell lines must avoid the use of animal serum and/or animal feeder cell lines. Safe and fast approaches to producing hES cell lines based on recent research advances in both humans and animals have been suggested.
人类胚胎干细胞（hES细胞）有潜力分化为任何所需的细胞，并可用于某些疾病的细胞替代疗法。然而，现有的hES细胞系因被其他生物制品污染，不适用于这些疗法。为了生产出用于治疗目的的最安全的hES细胞系，建立hES细胞系的所有步骤都必须避免使用动物血清和/或动物饲养细胞系。基于人类和动物近期的研究进展，已经提出了安全、快速地生产hES细胞系的方法。
