He Li-Qun, Cai Gan
Department of Nephrology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China.
Zhong Xi Yi Jie He Xue Bao. 2005 Jul;3(4):270-3. doi: 10.3736/jcim20050407.
To evaluate the effects of Jianpi Qinghua Recipe (JPQHR) on chronic renal failure with syndrome of dampness-heat due to spleen deficiency and its mechanism.
One hundred and six patients were randomly divided into two groups: control group (53 patients treated with routine therapy) and JPQHR-treated group (53 patients treated with routine therapy and JPQHR).
Routine therapy combined with JPQHR could improve symptoms. The serum creatinine, blood urea nitrogen, triglyceride and low density lipoprotein decreased significantly in the JPQHR-treated group as compared with those in the control group (P<0.05), while the number of erythrocyte rosette-forming cells increased significantly in the JPQHR-treated group as compared with those in the control group (P<0.05).
Routine therapy combined with JPQHR can significantly decrease blood lipid level and strengthen cellular immune system, so it can lower the urine protein in the early and middle stages of chronic renal failure and improve renal function.
评价健脾清化方（JPQHR）对脾虚湿热型慢性肾衰竭的疗效及其作用机制。
106例患者随机分为两组：对照组（53例采用常规疗法治疗）和健脾清化方治疗组（53例采用常规疗法加健脾清化方治疗）。
常规疗法联合健脾清化方可改善症状。与对照组相比，健脾清化方治疗组血清肌酐、血尿素氮、甘油三酯和低密度脂蛋白显著降低（P<0.05），而健脾清化方治疗组红细胞玫瑰花结形成细胞数量较对照组显著增加（P<0.05）。
常规疗法联合健脾清化方可显著降低血脂水平，增强细胞免疫系统，从而降低慢性肾衰竭早中期尿蛋白，改善肾功能。
