Andreyev J
Department of Medicine and Therapeutics, Imperial College Faculty of Medicine, Chelsea and Westminster Hospital, 369 Fulham Rd, London SW10 9NH, UK.
Gut. 2005 Aug;54(8):1051-4. doi: 10.1136/gut.2004.062596.
Radiation induced bowel damage affects 6000 individuals annually in the UK, with a negative impact on quality of life. Our understanding of how to treat these patients is dismally lacking an evidence base. Fibrosis seems to be the unifying underlying cause for most symptoms. Progress in understanding the development and treatment of fibrosis in these patients might have important consequences for patients with other causes of fibrosis in the gastrointestinal tract.
在英国,每年有6000人受到辐射诱发的肠道损伤影响,这对生活质量产生负面影响。我们对如何治疗这些患者的了解严重缺乏证据基础。纤维化似乎是大多数症状的共同潜在原因。在了解这些患者纤维化的发展和治疗方面取得进展,可能会对患有其他胃肠道纤维化病因的患者产生重要影响。