5-羟色胺3受体拮抗剂可改善疲劳：潜力巨大，了解却少！
5-HT3 receptor antagonists ameliorate fatigue: so much potential, so little knowledge!
作者信息
Barnes N M
机构信息
Cellular and Molecular Neuropharmacology Research Group, Department of Pharmacology, Division of Neuroscience, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
出版信息
Gut. 2005 Aug;54(8):1056-7. doi: 10.1136/gut.2004.063545.
Abstract
There is growing evidence that 5-HT3 receptor blockade will benefit patients with fatigue. Further research is needed to determine the mechanism underlying this widespread clinically important symptom and therapies may be derived from targeting the 5-HT system.
摘要
越来越多的证据表明，5-羟色胺3（5-HT3）受体阻断将使疲劳患者受益。需要进一步研究以确定这种广泛存在的具有临床重要性的症状背后的机制，并且治疗方法可能源于针对5-羟色胺系统。
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