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鼻及鼻窦非霍奇金淋巴瘤:一例报告

Non-Hodgkin's lymphoma of the nose and paranasal sinuses: a case report.

作者信息

Kandoğan Tolga, Olgun Levent, Aydar Levent, Ozlem Sezgin

机构信息

Department of Otolaryngology, SSK Izmir Training Hospital, Izmir, Turkey.

出版信息

Kulak Burun Bogaz Ihtis Derg. 2004;12(3-4):95-8.

Abstract

Primary non-Hodgkin lymphoma (NHL) of the nasal cavity is a rare neoplasm. They account for about 0.17-2% of all cases of NHL and 5.8% of all malignant neoplasms of the sinonasal region in adults. A 37-year-old male patient presented with left-sided nasal obstruction and headache which appeared a couple of weeks before the admission. Nasal examination revealed a massive polyposis. After medical therapy with corticosteroids, neither the polyposis nor his complaints showed regression; thus, he underwent a nasal polypectomy operation. Biopsy results indicated an inflammatory nasal polyp. Two weeks later, a rapidly progressive facial swelling, especially in the left periorbital area and blurred vision occurred. Second biopsy, which was also taken from the left nasal cavity suggested again an inflammatory nasal polyp. To rule out any possible malignancy, a third biopsy was conducted in the left maxillary sinus which indicated T/NK cell lymphoma of the sinonasal tract.

摘要

鼻腔原发性非霍奇金淋巴瘤(NHL)是一种罕见的肿瘤。它们约占所有NHL病例的0.17 - 2%,占成人鼻窦区域所有恶性肿瘤的5.8%。一名37岁男性患者入院前几周出现左侧鼻塞和头痛。鼻腔检查发现大量息肉样病变。使用皮质类固醇进行药物治疗后,息肉样病变和他的症状均未消退;因此,他接受了鼻息肉切除术。活检结果显示为炎性鼻息肉。两周后,面部迅速肿胀,尤其是左侧眶周区域,视力模糊。再次从左侧鼻腔进行活检,结果再次提示为炎性鼻息肉。为排除任何可能的恶性肿瘤,在左上颌窦进行了第三次活检,结果显示为鼻窦T/NK细胞淋巴瘤。

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