Torre Valerio, Bucolo Sebastiano, Giordano Carlo, Cicciarello Rocco, Cavallari Vittorio, Garofalo Loredana, Beatrice Fabio
Unit of pathology, F.Veneziale Hospital, Isernia, Italy.
J Oral Pathol Med. 2005 Aug;34(7):390-6. doi: 10.1111/j.1600-0714.2005.00319.x.
Tobacco smoke is a well-known source of toxic, mutagenic and carcinogenic agents. The aim of the present preliminary study was to investigate the effects of cigarette smoking on lymphoid and non-lymphoid tonsillar tissue.
The study group consisted of 12 smoker and 10 non-smoker patients complaining recurrent tonsillitis. Clinical data, histological findings and scanning electron microscopic analyses were considered. To the best of our knowledge, such an approach has not been previously adopted in a similar experimental model.
Smoker patients showed a longer history of recurrent tonsillitis, difficulties in clinical management and evident morphostructural changes than non-smokers.
These preliminary results suggest a possible interference of cigarette smoking with the therapy response as well as a possible role of tobacco smoke in impairment of inflammatory response. Results are critically analysed and discussed. Literature data on this subject are reviewed.
烟草烟雾是众所周知的有毒、致突变和致癌物质的来源。本初步研究的目的是调查吸烟对扁桃体淋巴组织和非淋巴组织的影响。
研究组由12名吸烟和10名不吸烟且患有复发性扁桃体炎的患者组成。考虑了临床数据、组织学结果和扫描电子显微镜分析。据我们所知，在类似的实验模型中以前尚未采用过这种方法。
与不吸烟者相比，吸烟患者复发性扁桃体炎病史更长，临床管理困难，且有明显的形态结构变化。
这些初步结果表明吸烟可能干扰治疗反应，以及烟草烟雾在炎症反应受损中可能起的作用。对结果进行了批判性分析和讨论。回顾了关于该主题的文献数据。
