Xiang J, Holowka S, Ishii R, Wilson D, Chuang S
Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada.
Neurol Clin Neurophysiol. 2004 Nov 30;2004:106.
Our previous studies have demonstrated that there is a motion-related magnetic response evoked by moving sound but not stationary sound. The motion-related response reflects the dynamic activities of brain processing of auditory motion. This study focuses on the effect of attention on the response. Six normal hearing subjects were studied using a 151-channel whole-cortex magnetoencephalography (MEG) system. Four sound stimuli were designed: two sounds moved from left to right (rightward) and the other two sounds moved from right to left (leftward). Two sounds moving in the same direction were separated with an attention task. The attention task was a mathematical calculation. The results showed that when subjects listened to the moving sound, there was a clearly auditory motion related response at a latency of 649 +/- 14.2 ms. However, when subjects were doing the calculation while listening to the moving sounds, the motion related response completely disappeared. Strikingly, there was a dent at a latency of 600 ms. To our knowledge, this is probably the first study showing a neuromagnetic response which can be clearly elicited or inhibited by an attention task. We consider that the motion related response has the potential to be an objective index for the study of attention.
我们之前的研究表明，移动的声音会诱发与运动相关的磁反应，而静止的声音则不会。与运动相关的反应反映了大脑对听觉运动处理的动态活动。本研究聚焦于注意力对该反应的影响。使用151通道全脑磁脑图（MEG）系统对6名听力正常的受试者进行了研究。设计了四种声音刺激：两种声音从左向右移动（向右），另外两种声音从右向左移动（向左）。在同一方向移动的两种声音被一个注意力任务分隔开。注意力任务是进行数学计算。结果显示，当受试者聆听移动的声音时，在649±14.2毫秒的潜伏期出现了明显的与听觉运动相关的反应。然而，当受试者在聆听移动声音的同时进行计算时，与运动相关的反应完全消失。令人惊讶的是，在600毫秒的潜伏期出现了一个凹陷。据我们所知，这可能是第一项表明神经磁反应可被注意力任务清晰诱发或抑制的研究。我们认为，与运动相关的反应有可能成为研究注意力的一个客观指标。
