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精神科遗传学:对精神科医生的知识、观点及实践模式的一项调查。

Psychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns.

作者信息

Finn Christine T, Wilcox Marsha A, Korf Bruce R, Blacker Deborah, Racette Stephanie R, Sklar Pamela, Smoller Jordan W

机构信息

Department of Psychiatry, the Psychiatric Genetics Program in Mood and Anxiety Disorders, Massachusetts General Hospital, Boston, Mass. 02115, USA.

出版信息

J Clin Psychiatry. 2005 Jul;66(7):821-30. doi: 10.4088/jcp.v66n0703.

Abstract

OBJECTIVE

Knowledge about the genetic basis of psychiatric illness is growing rapidly, and psychiatrists may be called upon to incorporate this information into clinical practice. The goal of this study was to assess psychiatrists' familiarity with and attitudes toward genetic information.

METHOD

We surveyed 844 participants, the majority of whom were psychiatrists, attending a continuing medical education course in the fall of 2002 and measured knowledge, opinions, and current practice patterns in regard to psychiatric genetics.

RESULTS

Responses were received from 352 psychiatrists (54% of those surveyed). Most psychiatrists correctly answered fewer than half of survey items assessing general and psychiatric genetic knowledge. While 83% considered it their role to discuss genetic information with patients and families, fewer than 25% felt prepared or competent to do so. In response to hypothetical questions regarding genetic testing, a substantial proportion of psychiatrists indicated willingness to use such tests for diagnostic clarification, as well as presymptomatic and even prenatal risk prediction. The majority of respondents expressed interest in further genetics education.

CONCLUSIONS

Our results suggest that psychiatrists view genetic information as clinically relevant, but have limitations in knowledge that may impact the incorporation of psychiatric genetics into clinical practice.

摘要

目的

关于精神疾病遗传基础的知识正在迅速增长,精神科医生可能需要将这些信息纳入临床实践。本研究的目的是评估精神科医生对遗传信息的熟悉程度和态度。

方法

我们对844名参与者进行了调查,其中大多数是精神科医生,他们参加了2002年秋季的继续医学教育课程,并测量了他们在精神遗传学方面的知识、观点和当前的实践模式。

结果

收到了352名精神科医生的回复(占调查对象的54%)。大多数精神科医生正确回答的评估一般和精神遗传知识的调查项目不到一半。虽然83%的人认为与患者及其家属讨论遗传信息是他们的职责,但不到25%的人觉得自己有准备或有能力这样做。在回答关于基因检测的假设性问题时,相当一部分精神科医生表示愿意使用此类检测来明确诊断,以及进行症状前甚至产前风险预测。大多数受访者表示有兴趣接受进一步的遗传学教育。

结论

我们的结果表明,精神科医生认为遗传信息与临床相关,但在知识方面存在局限性,这可能会影响精神遗传学在临床实践中的应用。

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