Valsangiacomo Büchel Emanuela R, DiBernardo Stefano, Bauersfeld Urs, Berger Felix
Division of Paediatric Cardiology, University Children's Hospital Zurich, Steinwiesstr.75, 8032 Zurich, Switzerland.
Int J Cardiovasc Imaging. 2005 Apr-Jun;21(2-3):313-22. doi: 10.1007/s10554-004-4017-y.
Catheter-guided interventions are increasingly used for relief of lesions in patients with congenital heart disease. Exact anatomical imaging with measurement of the vascular structures is crucial in the planning of such interventions. This can be provided non-invasively and without radiation by contrast-enhanced MR angiography (CE-MRA).
To evaluate the accuracy of the measurements of the vessels obtained by CE-MRA in comparison to those obtained by conventional X-ray angiography (XRA).
Measurements of the diameters of aorta and pulmonary arteries were performed retrospectively and blinded on the CE-MRA and XRA images, in comparable locations. The limits of agreement between the two methods were calculated.
Twenty-one CE-MRA and XRA were performed in 20 children with congenital heart disease, median age 4 years (1 day-13 years), weight 18 kg (3.2-74 kg). The time interval between CE-MRA and XRA was 2.6 +/- 2.3 months. A total of 98 measurements, 38 of the aorta and 60 of the pulmonary arteries were performed on the images obtained by each technique. The correlation between CE-MRA and XRA measurements was excellent, r = 0.97, p < 0.0001. The mean difference between the two techniques was 0.018 +/- 1.1 mm; the limits of agreement -2.14 and + 2.18 mm. Similar agreement was found for measures of the aorta (r = 0.97, mean difference 0.20 +/- 1.08 mm) and of the pulmonary arteries (r = 0.97, mean difference 0.048 +/- 0.89 mm).
CE-MRA provides accurate quantitative anatomical information, which highly agrees with XRA data, and can therefore be used for planning catheter-guided procedures.
导管引导干预越来越多地用于缓解先天性心脏病患者的病变。在规划此类干预措施时，精确的解剖成像以及血管结构的测量至关重要。对比增强磁共振血管造影（CE-MRA）可以无创且无辐射地提供这种成像。
评估CE-MRA获得的血管测量值与传统X射线血管造影（XRA）获得的测量值相比的准确性。
回顾性地对CE-MRA和XRA图像上可比位置的主动脉和肺动脉直径进行测量，测量过程设盲。计算两种方法之间的一致性界限。
对20例先天性心脏病患儿进行了21次CE-MRA和XRA检查，患儿中位年龄4岁（1天至13岁），体重18 kg（3.2至74 kg）。CE-MRA和XRA之间的时间间隔为2.6±2.3个月。在每种技术获得的图像上总共进行了98次测量，其中主动脉38次，肺动脉60次。CE-MRA和XRA测量之间的相关性极佳，r = 0.97，p <0.0001。两种技术之间的平均差异为0.018±1.1 mm；一致性界限为-2.14和+2.18 mm。在主动脉测量（r = 0.97，平均差异0.20±1.08 mm）和肺动脉测量（r = 0.97，平均差异0.048±0.89 mm）中发现了类似的一致性。
CE-MRA提供准确的定量解剖信息，与XRA数据高度一致，因此可用于规划导管引导手术。
