Homan M R, Gharib H, Goellner J R
Division of Endocrinology, Metabolism and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905.
Head Neck. 1992 Mar-Apr;14(2):113-8. doi: 10.1002/hed.2880140207.
The finding of papillary carcinoma in a neck mass usually leads to the presumptive diagnosis of metastatic thyroid carcinoma, with total thyroidectomy revealing the primary tumor. We report five cases of metastatic papillary carcinoma of the neck. The primary tumor in three of the cases was found to be nonthyroidal; two being discovered only after thyroidectomy failed to reveal a primary cancer. In the two thyroidal neoplasms, pathologic examination of the thyroid demonstrated only minimal tumor in one case and no detectable tumor in the other. These cases illustrate the pitfalls of diagnosis and treatment of these tumors and the utility of antithyroglobulin immunostaining in such cases.
颈部肿块中发现乳头状癌通常会导致转移性甲状腺癌的初步诊断，全甲状腺切除术后可发现原发性肿瘤。我们报告了5例颈部转移性乳头状癌病例。其中3例的原发性肿瘤被发现并非来自甲状腺；有2例是在甲状腺切除术后未发现原发性癌症的情况下才被发现。在2例甲状腺肿瘤中，1例甲状腺的病理检查仅发现极少量肿瘤，另1例未检测到肿瘤。这些病例说明了这些肿瘤诊断和治疗中的陷阱以及抗甲状腺球蛋白免疫染色在此类病例中的作用。
