Dong Yong-Li, Gao Lu, Yang Xiao-Xia, Wen Bo, Yang Zhi-Li, Tang Wen-Ru, Cheng Bao-Wen, Zheng Bing-Rong, Li Kai-Yuan, Xiao Chun-Jie
Human Genetics Center of Yunnan University, Kunming 650091, China.
Yi Chuan Xue Bao. 2005 May;32(5):450-6.
In the same ethnic group, people residing at different places may have genetic difference. The difference can be the results of migration and admixture events happened in history. To clarify the genetic relationship and micro-evolution of two Bai ethnic populations residing in Yunnan and Hunan province respectively,we investigated their genetic difference from paternal and maternal genealogy with six other ethnic groups as outgroups. Fourteen loci from mtDNA and thirteen loci from Y chromosome were selected for genotyping using PCR-RFLP methods. Result showed that H6 and H8 are the same dominant Y chromosome haplotypes in two Bai groups. However,the distribution of mtDNA haplogroups showed difference between two Bai populations. D, B, M8 are the predominant haplogroups in Hunan Bai ethnic population, whereas M, G, F are dominant in Yunnan Bai ethnic population. Principal Component (PC) analysis based on the Y chromosome haplotypes showed that two Bai ethic populations cluster together. It shows a close paternal genetic relationship between two Bai ethnic populations. From the mtDNA PC plot, it is clear that Hunan Bai is close to Hunan Han and Tujia, whereas Yunnan Bai is close to ethnic groups living in Yunnan province. The difference of mtDNA haplogroup distribution in two Bai people may reflect the maternal gene flow between ethnic groups living in Hunan province after the ancestors of Hunan Bai migrated from Yunnan province to Hunan province 800 years ago.
在同一民族中，居住在不同地方的人群可能存在基因差异。这种差异可能是历史上发生的迁徙和混合事件的结果。为了阐明分别居住在云南省和湖南省的两个白族人群的遗传关系和微进化情况，我们以其他六个民族作为外群，从父系和母系谱系方面研究了他们的基因差异。使用PCR-RFLP方法对线粒体DNA的14个位点和Y染色体的13个位点进行基因分型。结果显示，H6和H8是两个白族群体中相同的主要Y染色体单倍型。然而，两个白族群体中线粒体DNA单倍群的分布存在差异。D、B、M8是湖南白族人群中的主要单倍群，而M、G、F在云南白族人群中占主导地位。基于Y染色体单倍型的主成分（PC）分析表明，两个白族群体聚在一起。这表明两个白族群体在父系遗传关系上较为密切。从线粒体DNA的PC图可以看出，湖南白族与湖南汉族和土家族接近，而云南白族与居住在云南省的民族接近。两个白族人群中线粒体DNA单倍群分布的差异可能反映了800年前湖南白族的祖先从云南省迁徙到湖南省后，湖南各民族之间的母系基因流动情况。
