当前肾癌的临床试验。
Current clinical trials in renal cell carcinoma.
作者信息
Sokoloff Mitchell H, Daneshmand Siamak, Ryan Christopher W
机构信息
Department of Surgery, Section of Urologic Oncology, Division of Urology and Renal Transplantation, Portland, OR 97239-3098, USA.
出版信息
Urol Oncol. 2005 Jul-Aug;23(4):289-92. doi: 10.1016/j.urolonc.2005.05.007.
The treatment of renal cell carcinoma remains primarily surgical. Consequently, it is not surprising that urologists have been active in the design and operation of clinical trials for patients with kidney cancer. Currently, clinical trial efforts of the urologic community are focused on the adjuvant setting in patients undergoing nephrectomy at high risk for recurrence or metastasis. As newer agents become available and are applied earlier during the course of the disease, the involvement of urologists in clinical trials in renal cell carcinoma will increase. This review highlights several key trials currently available for patients with kidney cancer.
肾细胞癌的治疗主要仍以手术为主。因此，泌尿外科医生积极参与肾癌患者临床试验的设计与实施也就不足为奇了。目前，泌尿外科领域的临床试验工作主要集中在对复发或转移高危的接受肾切除术患者的辅助治疗方面。随着更新的药物问世并在疾病进程中更早应用，泌尿外科医生在肾细胞癌临床试验中的参与度将会增加。本综述重点介绍了目前可供肾癌患者使用的几项关键试验。
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