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本文引用的文献

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A randomized controlled trial of intravenous N-acetylcysteine for the prevention of contrast-induced nephropathy after cardiac catheterization: lack of effect.一项关于静脉注射N-乙酰半胱氨酸预防心脏导管插入术后造影剂肾病的随机对照试验：无效。
Am Heart J. 2004 Sep;148(3):422-9. doi: 10.1016/j.ahj.2004.03.041.
2
Effect of N-acetylcysteine for prevention of contrast nephropathy in patients with moderate to severe renal insufficiency: a randomized trial.N-乙酰半胱氨酸对中重度肾功能不全患者预防造影剂肾病的作用：一项随机试验。
Am J Kidney Dis. 2004 May;43(5):801-8. doi: 10.1053/j.ajkd.2004.01.010.
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Systematic review of the impact of N-acetylcysteine on contrast nephropathy.N-乙酰半胱氨酸对造影剂肾病影响的系统评价
Kidney Int. 2004 Apr;65(4):1366-74. doi: 10.1111/j.1523-1755.2004.00516.x.
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N-acetylcysteine for the prevention of radiocontrast induced nephropathy: a meta-analysis of prospective controlled trials.
J Am Soc Nephrol. 2004 Mar;15(3):761-9. doi: 10.1097/01.asn.0000116241.47678.49.
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Standard vs double dose of N-acetylcysteine to prevent contrast agent associated nephrotoxicity.标准剂量与双倍剂量N-乙酰半胱氨酸预防造影剂相关肾毒性的比较
Eur Heart J. 2004 Feb;25(3):206-11. doi: 10.1016/j.ehj.2003.11.016.
6
The value of N-acetylcysteine in the prevention of radiocontrast agent-induced nephropathy seems questionable.N-乙酰半胱氨酸在预防放射性造影剂所致肾病方面的价值似乎存在疑问。
J Am Soc Nephrol. 2004 Feb;15(2):407-10. doi: 10.1097/01.asn.0000106780.14856.55.
7
N-acetylcysteine in the prevention of radiocontrast-induced nephropathy.N-乙酰半胱氨酸预防造影剂所致肾病
J Am Soc Nephrol. 2004 Feb;15(2):251-60. doi: 10.1097/01.asn.0000107562.68920.92.
8
Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials.N-乙酰半胱氨酸预防慢性肾病患者造影剂肾病：一项随机对照试验的荟萃分析
Am J Kidney Dis. 2004 Jan;43(1):1-9. doi: 10.1053/j.ajkd.2003.09.009.
9
Meta-analysis of randomized clinical trials on the usefulness of acetylcysteine for prevention of contrast nephropathy.
Am J Cardiol. 2003 Dec 15;92(12):1454-8. doi: 10.1016/j.amjcard.2003.08.059.
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Water for contrast-induced nephropathy? A thirst for knowledge.用于预防造影剂肾病的水？求知若渴。
J Invasive Cardiol. 2003 Dec;15(12):703-5.

N-乙酰半胱氨酸预防放射性造影剂所致肾毒性：剂量和给药途径的重要性

N-acetylcysteine for prevention of radiocontrast induced nephrotoxicity: the importance of dose and route of administration.

作者信息

Shalansky S J, Pate G E, Levin A, Webb J G

出版信息

Heart. 2005 Aug;91(8):997-9. doi: 10.1136/hrt.2004.053579.

DOI:10.1136/hrt.2004.053579
PMID:16020580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1769030/
Abstract

Dose and route of administration of N-acetylcysteine are key factors to consider when evaluating whether this agent is effective in preventing radiocontrast induced nephropathy.

摘要

在评估N-乙酰半胱氨酸是否能有效预防造影剂诱导的肾病时，其给药剂量和途径是需要考虑的关键因素。