Cedrón Cheng Hugo, Piscoya Rivera Alejandro, Bussalleu Rivera Alejandro, Huerta-Mercado Tenorio Jorge
Servicio de Gastroenterología, Hospital Nacional Cayetano Heredia.
Rev Gastroenterol Peru. 2005 Apr-Jun;25(2):206-9.
We report the case of a 24 years old, nineteen weeks pregnant that develops pictures of severe hypoglycemia as first manifestation of primary hepatocarcinoma by hepatitis B. The great increase of the alpha fetoprotein was diagnostic. We reviewed the Literature and comment the hypoglycemic effect as a paraneoplasic manifestation by the increase of the growth-factor similar to insulin II of tumor origin, with low insulin levels.
我们报告了一例24岁、孕19周的患者,其以严重低血糖症状为首发表现,最终诊断为乙型肝炎所致原发性肝癌。甲胎蛋白大幅升高有助于诊断。我们回顾了相关文献,并对低血糖效应进行了评论,认为这是一种副肿瘤综合征表现,其机制为肿瘤来源的类似胰岛素II的生长因子增加,而胰岛素水平较低。