Khor T H
Mount Elizabeth Oncology Centre, 3 Mount Elizabeth, Singapore 228510.
Ann Acad Med Singap. 2005 Jun;34(5):399-404.
The Lecture covers the author's personal experience in brachytherapy in radiation oncology, beginning with low-dose rate (LDR) treatments using 226Ra "hot" sources, in the 1960s and early 1970s, through manual afterloading for treating gynaecological cancers with the same sources in the 1970s and 1980s, to high-dose rate (HDR) remote afterloading on a microSelectron HDR machine, from 1989 on. This progression in brachytherapy is discussed, and specific applications to various tumour sites are presented, including long-term results of a personal series of 106 patients with cancer of the uterine cervix, treated with radiotherapy incorporating HDR brachytherapy. The Lecture rounds off with an unusual case of equine sarcoid, treated with a postoperative implant, using 192Ir LDR brachytherapy.
本次讲座涵盖了作者在放射肿瘤学近距离放射治疗方面的个人经历，始于20世纪60年代和70年代初使用226Ra“热”源的低剂量率（LDR）治疗，到70年代和80年代使用相同源通过手动后装治疗妇科癌症，再到1989年起在microSelectron HDR机器上进行的高剂量率（HDR）远程后装。讨论了近距离放射治疗的这一发展过程，并介绍了其在各种肿瘤部位的具体应用，包括106例子宫颈癌患者采用含HDR近距离放射治疗的放疗的个人系列长期结果。讲座最后介绍了一例不寻常的马肉瘤病例，采用术后植入192Ir LDR近距离放射治疗。
