一种用于制备含阿米卡星的高粘度滴眼液的方法。
A method for the obtaining of increased viscosity eye drops containing amikacin.
作者信息
Sikora Adam, Oszczapowicz Irena, Tejchman Bozena, Grzechnik Małgorzata
机构信息
Institute of Biotechnology and Antibiotics, 5 Starościńska Str., 02-516 Warsaw.
出版信息
Acta Pol Pharm. 2005 Jan-Feb;62(1):31-7.
PMID:16022491
Abstract
A method for the obtaining of increased viscosity (3.6-52.5 cP) eye drops, containing amikacin-aminoglycoside antibiotic and as increasing viscosity agents: polivinyl alkohol, hydroxyethylcellulose or sodium hyaluronate was elaborated. Physicochemical and biological properties of these eye drops were determined.
摘要
一种制备粘度增加（3.6 - 52.5厘泊）的滴眼液的方法被研发出来，该滴眼液含有阿米卡星（一种氨基糖苷类抗生素）以及作为增稠剂的聚乙烯醇、羟乙基纤维素或透明质酸钠。测定了这些滴眼液的物理化学性质和生物学性质。
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