Leger J, Bouveret P, Swynghedauw B
Biochimie. 1979;61(7):803-5. doi: 10.1016/s0300-9084(79)80274-6.
Tropomyosin, one of the proteins regulating the sarcomere, was prepared from pig heart and rabbit skeletal muscles. The effect of these two different tropomyosins was studied between 0.5 and 10 mM of Mg2+ at a constant ATP concentration (1 mM) on reconstituted actomyosin prepared from pig heart myosin and rabbit skeletal actin. Cardiac and skeletal tropomyosin both activated the ATPase at low Mg2+ concentrations and inhibited it above 3 mM. The pig heart and rabbit skeletal tropomyosins which contain two isomers, alpha alpha and alpha beta, respectively has very similar effects on actomyosin ATPase.
原肌球蛋白是调节肌节的蛋白质之一，从猪心脏和兔骨骼肌中提取。在1 mM的恒定ATP浓度下，研究了这两种不同的原肌球蛋白在0.5至10 mM Mg2+浓度范围内对由猪心脏肌球蛋白和兔骨骼肌肌动蛋白重构的肌动球蛋白的影响。心脏和骨骼肌原肌球蛋白在低Mg2+浓度下均激活ATP酶，在3 mM以上则抑制ATP酶。分别含有两种异构体αα和αβ的猪心脏和兔骨骼肌原肌球蛋白对肌动球蛋白ATP酶的作用非常相似。
