Oxford Lance E, McClay John
Department of Otorhinolaryngology-Head and Neck Surgery, University of Texas-Southwestern Medical Center, Dallas 75390-9035, USA.
Otolaryngol Head Neck Surg. 2005 Jul;133(1):32-7. doi: 10.1016/j.otohns.2005.03.020.
To review the demographic, microbiologic, and outcome data for children with complications of acute sinusitis.
Retrospective review of children admitted with complications of acute sinusitis from January 1995 to July 2002 to a tertiary care children's hospital.
One hundred four patients were reviewed with the following complications: orbital cellulitis (51), orbital abscesses (44), epidural empyemas (7), subdural empyemas (6), intracerebral abscesses (2), meningitis (2), cavernous sinus thrombosis (1), and Pott's puffy tumors (3). Sixty-six percent were males (P < 0.001), and 64.4% presented from November to March (P < 0.001). Patients with isolated orbital complications were younger than patients with intracranial complications (mean, 6.5 versus 12.3 years), had a shorter stay (mean, 4.2 versus 16.6 days), and had shorter duration of symptoms (mean, 5.4 versus 14.3 days; all P < 0.0001). Complete resolution was documented for 54/55 patients with restricted ocular motility, 7/8 with visual loss, 3/3 patients with a nonreactive pupil, 7/7 with neurological deficits, and 2/4 with seizures. The most common organism isolated was Streptococcus milleri (11/36 patients with surgical cultures). No mortalities occurred, and persistent morbidity occurred in 4 patients (3.8%).
Despite significant deficits on presentation, permanent morbidity was low. Streptococcus milleri is a common pathogen with complications of sinusitis in children.
回顾急性鼻窦炎并发症患儿的人口统计学、微生物学及预后数据。
对1995年1月至2002年7月在一家三级儿童专科医院因急性鼻窦炎并发症入院的患儿进行回顾性研究。
共对104例患儿的以下并发症进行了评估:眶蜂窝织炎(51例)、眶脓肿(44例)、硬膜外积脓(7例)、硬膜下积脓(6例)、脑脓肿(2例)、脑膜炎(2例)、海绵窦血栓形成(1例)及波特氏浮肿性肿瘤(3例)。66%为男性(P<0.001),64.4%在11月至次年3月发病(P<0.001)。单纯眶部并发症患儿比颅内并发症患儿年龄小(平均年龄分别为6.5岁和12.3岁),住院时间短(平均分别为4.2天和16.6天),症状持续时间短(平均分别为5.4天和14.3天;所有P<0.0001)。54/55例眼球运动受限患儿、7/8例视力丧失患儿、3/3例瞳孔无反应患儿、7/7例神经功能缺损患儿及2/4例癫痫患儿均实现完全缓解。分离出的最常见病原体为米勒链球菌(手术培养的36例患儿中有11例)。无死亡病例,4例(3.8%)患儿出现持续性疾病。
尽管发病时存在明显缺陷,但永久性疾病发生率较低。米勒链球菌是儿童鼻窦炎并发症的常见病原体。