Ismail Hassan M, Simmons Christina, Pfortmiller Deborah
Department of Internal Medicine, East Tennessee State University/James Quillen College of Medicine, Johnson City, TN 37604, USA.
J Investig Med. 2005 Jan;53(1):31-6. doi: 10.2310/6650.2005.00003.
This study was conducted to test the hypothesis that internal medicine residents at a northeast Tennessee university clinic were not compliant with the latest National Cholesterol Educational Program Adult Treatment Panel (NCEP-ATP) guidelines in treating hyperlipidemia in patients with diabetes and coronary artery disease.
A retrospective medical record survey was conducted to evaluate residents' pattern in lowering low-density lipoprotein (LDL) cholesterol to below 100 mg/dL in patients with diabetes and coronary artery disease. The survey covered a 5-year period, from July 1998 to June 2003, and included 15 randomly chosen residents who were in training for 3 consecutive years. Charts were randomly selected from residents' clinics using International Classification of Diseases-9 codes for coronary artery disease or diabetes mellitus with hyperlipidemia. Five hundred fifty charts were reviewed. Only 41 (7.45%) met the inclusion criteria.
Analysis of data using Epi-Info 2002 (Centers for Disease Control and Prevention, Atlanta, GA) revealed that only 68.3% of patients with diabetes and coronary artery disease reached target LDL cholesterol levels. Of the patients who reached target levels, only 42.9% maintained them. Analysis of variance and chi-square tests revealed that the frequency of cholesterol measurement, but not the frequency of physicians' visits, was associated with a higher likelihood of reaching the target LDL level.
There was a suboptimal compliance among internal medicine residents in the frequency of screening for, reaching, and maintaining the target LDL cholesterol level, according to the latest NCEP-ATP guidelines, among high-risk patients with hyperlipidemias.
本研究旨在验证以下假设:田纳西州东北部一所大学诊所的内科住院医师在治疗糖尿病和冠状动脉疾病患者的高脂血症时,未遵循最新的美国国家胆固醇教育计划成人治疗小组(NCEP - ATP)指南。
进行了一项回顾性病历调查,以评估住院医师将糖尿病和冠状动脉疾病患者的低密度脂蛋白(LDL)胆固醇降至100 mg/dL以下的情况。该调查涵盖了1998年7月至2003年6月的5年时间,包括15名连续培训3年的随机选择的住院医师。使用国际疾病分类第9版代码,从住院医师诊所中随机选取冠状动脉疾病或伴有高脂血症的糖尿病病历。共审查了550份病历。只有41份(7.45%)符合纳入标准。
使用Epi - Info 2002(美国疾病控制与预防中心,佐治亚州亚特兰大)对数据进行分析后发现,只有68.3%的糖尿病和冠状动脉疾病患者达到了LDL胆固醇目标水平。在达到目标水平的患者中,只有42.9%维持住了该水平。方差分析和卡方检验显示,胆固醇测量频率而非医生就诊频率与达到LDL目标水平的较高可能性相关。
根据最新的NCEP - ATP指南,在内科住院医师中,针对高脂血症高危患者筛查、达到和维持LDL胆固醇目标水平的频率存在欠佳的依从性。