Chernov N V, Klochikhin A L, Markov G I
Vestn Otorinolaringol. 2005(2):52-4.
The authors present the results of treatment of 62 patients with locally advanced laryngeal cancer (LALC) stage III-IV (T3-4NOMO) treated in 1986-2000. The study was made of tracheostomy effects in laryngostenosis following radical operation (not tracheostomy as a stage of laryngectomy) on regional and distant metastasizing as well as on further growth, tumor recurrence and survival in treated patients with LALC. The authors conclude that tracheostomy conducted before radical surgery has a negative effect on heeling the postoperative wound, promotes regional metastasizing and tumor recurrence in patients with LALC, lowers 5-year survival.
作者展示了1986年至2000年间对62例局部晚期喉癌（LALC）III-IV期（T3-4N0M0）患者进行治疗的结果。该研究针对根治性手术后喉狭窄中的气管切开术效果（而非作为喉切除术一个阶段的气管切开术），对局部和远处转移以及LALC治疗患者的进一步生长、肿瘤复发和生存情况进行了研究。作者得出结论，根治性手术前进行的气管切开术对术后伤口愈合有负面影响，促进LALC患者的局部转移和肿瘤复发，降低5年生存率。
