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[色氨酸前体对猪肾上腺皮质应激反应性及行为反应的影响]

[Effect of a tryptophan lead on the swine adrenal cortex reactivity and behavioral response to stress].

作者信息

Morméde P, Dantzer R

出版信息

C R Seances Soc Biol Fil. 1979;173(3):569-75.

PMID:160272
Abstract

Behaviour and plasma corticosteroid levels were investigated in pigs preloaded with 50 to 200 mg/kg 1-tryptophan. The treatment did not influence reactions to frustation and had no effect on continuous avoidance responding. However the adrenal response to the stress of new environment concomitant with delivery of unavoidable shocks was decreased (fig. 1), as well as the behavioural response to a fear signal superimposed on a continuous avoidance paradigm (fig. 2). These results point out relatively specific psychotropic effects of a tryptophan load in pigs.

摘要

对预先加载50至200毫克/千克1-色氨酸的猪的行为和血浆皮质类固醇水平进行了研究。该处理不影响对挫折的反应,对持续回避反应也无影响。然而,伴随不可避免的电击传递,肾上腺对新环境应激的反应降低了(图1),并且对叠加在持续回避范式上的恐惧信号的行为反应也降低了(图2)。这些结果指出了色氨酸负荷对猪具有相对特定的精神otropic作用。 (注:原文中“psychotropic”可能有误,推测应为“psychotropic”,意为“精神otropic的” ,翻译时保留了原文错误拼写。)

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