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[产后大鼠暴露于铅所致的行为改变]

[Behavioral alterations induced by post-natal exposure of the rat to lead].

作者信息

Dantzer R, Camguilhem R

出版信息

C R Seances Soc Biol Fil. 1979;173(3):592-9.

PMID:160274
Abstract

The behaviour of rats exposed to various levels of lead acetate (0.5 ; 1 ; 2 and 4% in dam's diet) before weaning was recorded between 2 and 6 months of age. Higher locomotor and exploratory activities as well as better scores in active avoidance conditioning were observed in the 4% lead-treated rats. For lower doses, no behavioural alterations were recorded despite both detarded growth and increased mortality.

摘要

记录了断奶前暴露于不同水平醋酸铅(母鼠饮食中分别为0.5%、1%、2%和4%)的大鼠在2至6月龄之间的行为。在接受4%铅处理的大鼠中观察到更高的运动和探索活动,以及在主动回避条件反射测试中获得更好的分数。对于较低剂量,尽管出现生长迟缓以及死亡率增加,但未记录到行为改变。

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