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在个体间背景下研究个体衰老:老年期与年龄相关、与痴呆相关以及与死亡率相关的认知发展的典型路径。

Studying individual aging in an interindividual context: typical paths of age-related, dementia-related, and mortality-related cognitive development in old age.

作者信息

Lövdén Martin, Bergman Lars, Adolfsson Rolf, Lindenberger Ulman, Nilsson Lars-Göran

机构信息

Center for Lifespan Psychology, Max Planck Institute for Human Development, Lentzeallée 94, D-14195 Berlin, Germany.

出版信息

Psychol Aging. 2005 Jun;20(2):303-16. doi: 10.1037/0882-7974.20.2.303.

Abstract

This study has 2 objectives: (a) to explore typical paths of cognitive development associated with aging, terminal decline, and dementia and (b) to promote and illustrate an individual-oriented approach to the study of cognitive aging based on longitudinal panel data from a population-based sample (N = 500; age range-sub(T1)= 60-80, where T refers to time) tested at 3 occasions 5 years apart. Results document interindividual differences in multivariate patterns of change. Although cognitive changes generally covary, the present study indicates that subgroups of individuals develop along different paths characterized by selective changes in subsets of cognitive functions. Typical progression of dementia followed a developmental cascade from low declarative memory, via low functioning across all observed cognitive measures, to dementia diagnosis, and finally, death.

摘要

本研究有两个目标

(a)探索与衰老、临终衰退和痴呆症相关的认知发展典型路径;(b)基于来自一个基于人群的样本(N = 500;年龄范围 - 基线期(T1)= 60 - 80岁,其中T表示时间)的纵向面板数据,促进并说明一种以个体为导向的认知衰老研究方法,该样本在相隔5年的3个时间点进行了测试。结果记录了个体间变化的多变量模式差异。虽然认知变化通常相互关联,但本研究表明,个体亚组沿着不同路径发展,其特征是认知功能子集中的选择性变化。痴呆症的典型进展遵循从低陈述性记忆开始,经过所有观察到的认知测量指标的低功能状态,到痴呆症诊断,最终到死亡的发展级联过程。

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