Thompson J C, Ellison R, Gillett R, Badcoe L
Batchelar Animal Health Laboratory, PO Box 536, Palmerston North, New Zealand.
N Z Vet J. 1995 Apr;43(2):79-82. doi: 10.1080/00480169.1995.35854.
Thyrotropin releasing hormone (TRH) stimulation tests were carried out on a number of horses, including one clinically affected horse whose age and clinical signs suggested that a pituitary adenoma was most unlikely. The results of these tests indicated that, according to criteria published overseas, the majority of these horses had pituitary adenomas. The fact that clinically normal or affected horses may have marked increases in cortisol concentrations indicates that the TRH stimulation test is not suitable for the diagnosis of pituitary adenoma. Other tests, including alterations in glucose metabolism and, if available, ACTH measurements, are probably more useful for diagnosis. However, most diagnoses will probably rely upon the characteristic clinical signs.
对多匹马进行了促甲状腺激素释放激素（TRH）刺激试验，其中包括一匹临床患病马，其年龄和临床症状表明极不可能患有垂体腺瘤。这些试验结果表明，根据海外发表的标准，这些马中的大多数患有垂体腺瘤。临床正常或患病的马可能出现皮质醇浓度显著升高这一事实表明，TRH刺激试验不适用于垂体腺瘤的诊断。其他检查，包括葡萄糖代谢变化以及（如有条件）促肾上腺皮质激素（ACTH）测量，可能对诊断更有用。然而，大多数诊断可能仍依赖于特征性的临床症状。
